Tag Archives: rheumatoid arthritis

Rehab Journal Review: September 2014

PLOS One, August 2014

‘Did you read my sms thoughts?’ could be a reality sometime in future.  And the future might already be partly here. “Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies” sounds like a plot that could have been straight out of a James Cameron script book. 1) “Thoughts” from a person in Thiruvananthapuram, India, were recorded by surface EEG electrodes, 2) transferred via internet to France, 3) where they were “conveyed” to 3 people via Transcranial Magnetic Stimulation 4)  and they interpreted them!!! Already received extensive media coverage though almost none referenced the original article. Immense potential for persons with communication impairments. Immense potential for ethical quagmire.

Scandinavian Journal of Medicine & Science in Sports, Sep 2014

When a BMJ blog exclaims “Plantar fasciitis- important new research”, adding “an exciting new paper that is the first of its kind and represents a new treatment approach” I thought somebody has found a solution to the problem. The original paper  though was disappointing. The authors had compared high-load strength training against usual care of shoe inserts and stretches. Primary outcome of pain related symptoms were not different in both groups at 1 month, 6 months and 12 months. None of the secondary outcomes showed benefit with the new intervention. Yet, the authors conclude that their study “adds new evidence for the positive effect of a simple, progressive exercise protocol for (plantar fasciitis)”. Lessons: 1) In “conclusions”, state facts as they are. Not the way you want them to be. 2) It’s not dishonorable to report a negative study 3) do not go by authors’ conclusions, make your own from their tables and figures. 4) Do not be swayed by high regard for Scandinavian research or BMJ.

In the last month’s review, I’d promised a gift to anyone who could identify the glaring mistakes in another article on plantar fasciitis. There was just one response, and Abhita got it right. Cheers (finally, somebody responds).

Spinal Cord, September 2014

667 We’re getting closer to thanksgiving and having more than a fair share of Turkey this month. “Can spinal cord injury patients show a worsening in ASIA impairment scale classification despite actually having neurological improvement?” ask the Turkish authors before they launch their criticism on the limitations of ASIA Impairment Scale (AIS) Classification. The case examples they argue on are not uncommon, but that does not fully justify the article. We need to remember that the AIS has its advantages in allowing for a quick clinical survey, and that the Scale has never been a comprehensive assessment tool. Nothing beats a logical, complete neurological examination. We’ve had instances of post-graduate students found wanting in final exams if they fail to think beyond AIS.  “We’re getting addicted to methods, in the process forgetting basic things that we’re supposed to do”- said Dr. Pathmeswaran, a soft spoken public health Professor from Sri Lanka in his speech at the Hyderabad Cochrane Colloquium last week. How true.

693 Can abdominal massage administered by a electromechanical device reduce chronic constipation and other bowel problems in SCI? The Dutch authors found that the answer was ‘No’. Perhaps it was an oversimplification of the neurological issue to a mechanical one?

697 Acute abdomen in a person with high SCI has the potential to send you on a wild goose chase. Guarding & rigidity, the classical signs without which the surgeon would refuse to enter the OR, would be absent. Imaging studies would be as helpful as the search operations for the missing Malaysian Airlines plane. Risk to life could be very high, as we realized the hard way in one particular instance I remember.  This Turkish single center chart review study reports an incidence of about 4% (n=9) of acute abdominal emergencies in their cohort of 237 persons with SCI over five years. Gall bladder disease was the commonest cause. High clinical suspicion is warranted when there are subtle symptoms of unexplained gastroparesis and fever.

Practice tidbits

Liked in News

Workout while you work. One more of those why-didn’t-I-think-of-that innovations, the human hamster wheel might just set things in motion, literally, for the movement against ‘inactivity at workplace’.

dnews-files-2014-09-human-hamster-wheel-turns-up-670-jpg

Source: new.discovery.com

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Rehab Journal Review- May 2014

 

Loosener

Do you go blind and gaga over all the numbers thrown at you in the name of health statistics? Beware. This work on spurious calculations found that the number of films Niclas Cage appeared in inversely correlates with helicopter accidents killing occupants that year. Go figure.

 

Spinal Cord May 2014

368 The title makes it obvious this has to be from a Scandinavian database- “50 years follow-up on plasma creatinine levels after spinal cord injury”. Pulling out data of 119 persons with SCI, from as long back as 1945, the Danish authors conclude “The findings of this study support that p-creatinine is a poor detector of early renal deterioration, and until new tests like Cystatin C are further evaluated we recommend Cr-EDTA clearance as the gold standard in monitoring renal function in patients with SCI”. Though not by formal testing, we too found indicators of uselessness with blanket testing of creatinine in our annual SCI follow-up event attended by over 200 persons. Check creatinine only if there is specific suspicion of significant renal dysfunction.

 

400 This article from Toronto on Spinal Cord Essentials claims to be a qualitative+ semiquantitative one. The Canadian authors talk about their initiative to provide a comprehensive set of patient information leaflets that would be tailored to individual needs during and after the course of rehabilitation. And they’re free to download. Excellent. I sampled a couple of them, and I’m jealous. We are for long stuck at a much preliminary stage of hand-out preparations; I’m hopeful, though. As the popular jewellery ad concludes, hope is everything.

 

 

Archives of PMR, March 2014

506 A multidisciplinary team of co-authors from Alabama have reported the use of MRI Diffusion Tension Imaging to visualize what has long been suspected in motor recovery following stroke. “CorticoSpinal Tract disruption predicts the level of motor deficit, but not the response to Constraint-Induced therapy rehabilitation… suggests that the neural mechanisms critical for …recovery of motor function after damage to the CNS may differ substantially from the neural substrates that are critically involved in motor function before CNS damage”. “These findings emphasize the importance of a neural network consisting of bilateral sensorimotor cortices and hippocampus for response to CI therapy after damage to the CST, presumably acting as a neural compensatory mechanism”. Lesson: do not give up even if you see a bad MRI. Give at least one good trial targeting functional improvements. There are invisible compensatory mechanisms that could work.

 

515 Thesis alert. “Unrestricted educational grant from Allergan” in the conflicts section adds a bit of salt to the findings of this study which compared clinical (Modified Ashworth and Tardeau scales) and instrumented (surface EMG, torque) assessments of spasticity before and after Botox injections. As expected, clinical assessments did not predict response to Botox. What is interesting is that Instrumented assessment did. “In general, muscles with higher pathologic electromyography activation at baseline tended to be good responders and vice versa.” “…baseline RMS electromyography showed the highest sensitivity to identify responders. Conversely, the MAS and MTS have no predictive ability”.  It would be worth testing the utility of such EMG based tools in predicting response to different intervention modalities – casting, motor point injections, nerve blocks etc. Currently, we have none.

 

562 Thesis alert. An example of how not to interpret the effectiveness of an intervention. This systematic review on Comparative Effectiveness of Platelet-Rich Plasma Injections for Treating Knee Joint Cartilage Degenerative Pathology has included all the right type of figures and tables, but loses its credibility because it makes tall claims based on results pooled from very poor quality studies. Of the 16 included studies, there was just one study that used a control group (that received saline injections). Lesson: If logistics could be worked out, a properly done double blinded RCT is indicated and should be possible.

 

 

Archives of PMR, April 2014

642 Our own paper! Survival analysis of 490 persons with spinal cord injury in our follow-up area. 86% survival after 5 years, 58% after 25 years. The follow-up data over such a long period is very good for a private tertiary care hospital in India. Survival outcomes are good for a developing country, could be better. One major limitation was that we could not add a social context because of the lack of a denominator- total number of SCIs in the population under study over this period. That, for now, is beyond the scope of our institution.

 

Practice tid-bits

  • What type of exercises should be advised in knee osteoarthritis? This systematic review suggests focusing on “improving aerobic capacity, quadriceps muscle strength or lower extremity performance.” Supervised, three times a week seems to help better. The best part is, “Such programs have similar effect regardless of patient characteristics, including radiographic severity and baseline pain”.
  • Should Botox be injected only at specific points along muscles? This RCT says it doesn’t matter whether the injection is given at the so-called motor points at 20-30% length from origin, or way down below the middle of the gastrocs muscle in persons with stroke.
  • Do you ever ask female patients whether they have stress incontinence? You probably should, irrespective of what condition they present to you with. Not just patients, stress incontinence could be as common as 1 in 3 women aged 35-55. And the humble, do-it-anywhere pelvic floor exercises afford a definite and significant improvement in symptoms and quality of life, says this recently updated Cochrane review. For a better perspective, do read this no-nonsense post by a therapist. In your practice, remember to ask, and prescribe pelvic floor muscle training.

 

From twitter: Busy does not always mean productive.

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